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September 17, 2025International Journal of Innovative Technologies in Social ScienceOpen Access

Current Perspectives on the Management of Acute Graft-Versus-Host Disease in Pediatric Transplantation

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Authors

JPJulia Prabucka-MarciniakMBMichał BerezaMDMateusz Dembiński

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Overview

This review explores treatment options for graft-versus-host disease in pediatric HSCT patients, highlighting significant clinical gaps.

Key Points

  • Managing acute graft-versus-host disease (GVHD) remains a challenge in pediatric patients post-transplant.
  • Current prophylactic strategies include calcineurin inhibitors and methotrexate, indicating a need for tailored therapies.
  • The study synthesizes evidence on GVHD management through a systematic review, focusing on pediatric-specific needs.
  • Improving outcomes requires validation of treatments and exploration of novel agents for pediatric patients facing GVHD.

Cite This Study

Prabucka-Marciniak et al. (2025) studied this question.

synapsesocial.com/papers/68d43c79713b0b5dfea7bc91https://doi.org/10.31435/ijitss.3(47).2025.3734
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