September 16, 2025Clinical Interventions in AgingOpen Access

Impact of Combined Cognitive and Physical Impairments on Long-Term Prognosis in Elderly Cardiovascular Disease Patients: A Prospective Cohort Study

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Authors

YLYujia LiuSinopec (China)KCKe ChaiSecond Military Medical University TWTing WangFujian Medical University

Discussion

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Implication

Prospective cohort study shows increased mortality risk in elderly CVD patients with impairments, suggesting better assessment could improve outcomes.

Key Points

Combined physical and cognitive impairments significantly increase mortality risk in elderly cardiovascular disease patients.
Each 1-point improvement in SPPB and MMSE scores reduces mortality risk by 16.3% and 8.7%, respectively.
Cognitive function, particularly attention and calculation skills, is a strong predictor of survival in this patient population.
Routine assessment of cognitive and physical function is crucial to enhance clinical decision-making and patient management.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/68d43b18713b0b5dfea7bb55 https://doi.org/10.2147/cia.s535038

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Implication

Prospective cohort study shows increased mortality risk in elderly CVD patients with impairments, suggesting better assessment could improve outcomes.