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September 13, 2025

Clinical Efficacy of CAG Regimen Combined with Venetoclax, Chidamide, and Azacitidine in the Treatment of Elderly Patients with Acute Myeloid Leukemia.

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Authors

QLQingyang LiuJYJing YuMLMeng Li

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Overview

Clinical trial shows significant efficacy and safety of CAG regimen combined with venetoclax and chidamide for elderly AML patients, indicating promising treatment options.

Key Points

  • The overall response rate was 93.3%, with 11 out of 15 patients achieving complete response after treatment.
  • A follow-up analysis showed that all patients with detectable gene mutations achieved a composite response, supporting the treatment's efficacy.
  • The average recovery time for white blood cell count was 14.6 days post-chemotherapy, indicating effective patient monitoring.
  • Myelosuppression was the main adverse event, but serious complications were minimal during the treatment process.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/68d43b0f713b0b5dfea7b581https://doi.org/10.19746/j.cnki.issn.1009-2137.2025.04.003
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