The effect of Milk Fat Globule Membrane phospholipid supplementation on cognitive function in older adults with subjective memory complaints-a randomized, double blind, placebo-controlled trial

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Randomized controlled trial reveals effects of MFGM phospholipid on alertness in older adults, suggesting potential health benefits.

No significant treatment effects on cognitive function were found, indicating the complexity of cognitive health.
Subjective alertness improved in the high-dose phospholipid group, potentially enhancing cognitive testing performance.
Inflammation and cholesterol levels were reduced in both MFGM groups, which may support long-term cardiovascular health.
Increased Active B12 and reduction in Homocysteine levels suggest a positive impact on brain health from MFGM supplementation.

Zajac et al. (2025) studied this question.

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