Efficacy and safety of survodutide on glycemic control and weight loss in adults: A systematic review and meta‐analysis

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Discussion

Systematic review finds that survodutide improves glycemic control and weight loss in adults, highlighting potential gastrointestinal adverse events.

Survodutide significantly reduced HbA1c levels, indicating improved glycemic control in adults with diabetes.
Participants receiving higher doses of survodutide experienced greater reductions in body weight and waist circumference, enhancing treatment efficacy.
The analysis included six RCTs with over 1272 participants, ensuring robust findings on efficacy and safety parameters.
Despite its benefits, survodutide was associated with increased gastrointestinal adverse events, emphasizing the need for careful monitoring.

Xiao et al. (2025) studied this question.

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Systematic review finds that survodutide improves glycemic control and weight loss in adults, highlighting potential gastrointestinal adverse events.