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September 21, 2025

The effects of whole foods and dietary patterns on flow mediated dilation: a systematic review and meta-analysis of randomized controlled trials.

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Authors

NTNina M TrinquetNKNicole J. KellowRERafika Eviana

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Overview

Systematic review and meta-analysis reports that whole foods significantly improve endothelial function, suggesting dietary strategies for cardiovascular health.

Key Points

  • Whole foods and dietary patterns significantly improve flow mediated dilation, an indicator of endothelial function.
  • Meta-analysis considers 133 studies, including 102 analyzing whole food interventions and 31 focusing on dietary patterns.
  • Fruits, vegetables, soy, nuts, cocoa, and tea show consistent improvements in endothelial function across various trials.
  • Caution is advised due to moderate to low certainty of evidence and potential risk of bias in several studies.

Cite This Study

Trinquet et al. (2025) studied this question.

synapsesocial.com/papers/68d43afa713b0b5dfea7ad67https://doi.org/10.1016/j.ajcnut.2025.09.020
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