Red blood cell morphology changes in peripheral blood smear of type 2 diabetes mellitus patients

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T2DM patients showed significantly lower packed cell volume compared to controls, indicating possible structural changes in red blood cells.
Hypochromasia and anisocytosis were observed in the peripheral blood smears of 16% of T2DM patients, highlighting morphological abnormalities due to diabetes.
Hematological indices were measured using an automated analyzer in a case-control setting, involving healthy matched controls for comparison.
Findings support the inclusion of simple hematological parameters in monitoring diabetes complications and care.

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Case-control study finds altered RBC morphology and decreased hematocrit in T2DM patients, suggesting key hematological monitoring parameters.

Martina et al. (2025) studied this question.

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Case-control study finds altered RBC morphology and decreased hematocrit in T2DM patients, suggesting key hematological monitoring parameters.