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September 20, 2025Open Access

Whole-Genome Sequencing Uncovers Chromosomal and Plasmid-Borne Multidrug Resistance and Virulence Genes in Poultry-Associated Escherichia coli from Nigeria

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Authors

ECEjikeugwu ChikaCEChijioke EdehENEmmanuel Nwakaeze

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Overview

This analysis uncovers multidrug resistance and virulence genes in E. coli from Nigerian poultry, suggesting public health implications.

Key Points

  • Extensive multidrug resistance was confirmed in E. coli strain S3, with resistance to six of seven tested antibiotics.
  • Whole-genome sequencing identified numerous antibiotic resistance genes and plasmid types, indicating potential for horizontal gene transfer.
  • Virulence profiling detected several adhesion and toxin genes, suggesting the strain's capability to cause infections.
  • The findings highlight the need for stricter antimicrobial stewardship in poultry farming to reduce public health risks.

Cite This Study

Chika et al. (2025) studied this question.

synapsesocial.com/papers/68d439fa713b0b5dfea79d2chttps://doi.org/10.1101/2025.09.18.677015
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Also Consider

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  4. 4Genomic epidemiology and plasmid characterization of antimicrobial resistance and virulence in cattle <i>Escherichia coli</i> from China2025
  5. 5Multidrug Resistance of Escherichia coli From Poultry and Humans in contact: Serotyping, Resistance Genes, and Their Public Health Importance2025