The implementation of multidisciplinary interventions significantly reduced antibiotic use and resistance rates, indicating effective antimicrobial stewardship in the hospital.
Key Points
Antimicrobial usage rate dropped from 56.01% to 52.71% after the intervention.
The antibiotic use density decreased from 50.15 to 35.76 Defined Daily Doses per 100 patient-days.
Significant reductions in resistance were noted for both Klebsiella pneumoniae and Acinetobacter baumannii.
The findings demonstrate the potential of a multifaceted AMS strategy to combat antibiotic resistance.