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September 20, 2025Journal of Obstetrics and Gynaecology ResearchOpen Access

Real‐world clinical outcomes of patients with high‐risk endometrial cancer or endometrial carcinosarcoma in England: A retrospective cohort study

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Authors

VPVimalanand S. PrabhuMerck & Co., Inc., Rahway, NJ, USA (United States)ELErik LandfeldtIQVIA (United Kingdom)EREleanor RalphsIQVIA (United Kingdom)

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Implication

Retrospective cohort study estimates disease-free and overall survival in high-risk endometrial cancer patients, indicating significant recurrence rates.

Key Points

  • Overall survival from adjuvant therapy initiation was estimated at 8.85 years, indicating the long-term prognosis for patients.
  • Approximately 45% of participants experienced disease recurrence, underscoring the need for effective management strategies.
  • The study involved 6036 women and utilized data from Public Health England's National Cancer Registration and Analysis Service.
  • The results highlight the unmet medical needs and clinical burden faced by high-risk endometrial cancer patients.

Cite This Study

Prabhu et al. (2025) studied this question.

synapsesocial.com/papers/68d43913713b0b5dfea79114https://doi.org/10.1111/jog.70042
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