September 19, 2025

Electroacupuncture of specific acupoints of Shaoyang Meridian relieves progression of chronic migrain by down-regulating expression of P2Y12 receptor in rats.

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Electroacupuncture demonstrates improved pain thresholds in chronic migraine rats, suggesting down-regulation of P2Y12 and related proteins.

Electroacupuncture significantly increases pain thresholds in chronic migraine rats, indicating its potential as a treatment.
The decrease in the expression levels of P2Y12 receptors and related proteins supports the therapeutic effects of electroacupuncture.
Rats treated with electroacupuncture show superior changes in pain response compared to those receiving only medication or agonist treatments.
Insights from the study highlight electroacupuncture's role in reducing chronic migraine symptoms through neurobiological mechanisms.

Qiu et al. (2025) studied this question.

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Electroacupuncture demonstrates improved pain thresholds in chronic migraine rats, suggesting down-regulation of P2Y12 and related proteins.