Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 19, 2025Open Access

Comprehensive miRNA profiles revealing cancer-immunity

View Full Paper
Ask AI
Bookmark
Share

Authors

JYJiaqi YinYZYi ZhouZCZhenghong Chang

Discussion

Loading...

Member takes

Overview

This study identifies miRNAs impacting immune pathways in cancers, suggesting targeted therapies and new treatment strategies.

Key Points

  • The study identifies miRNAs regulating immune pathways in 32 cancer types, highlighting their therapeutic potential.
  • Key miRNA regulons like hsa-miR-130b-3p show significant correlations with immune cell infiltrations and tumor dynamics.
  • Utilizing GSEA-based and target gene computation, the research presents new insights into tumor-enhancing miRNA functions.
  • Marked differences in immune characteristics across two molecular subtypes of reproductive cancers underscore the need for personalized therapy.

Cite This Study

Yin et al. (2025) studied this question.

synapsesocial.com/papers/68d4370d713b0b5dfea77083https://doi.org/10.21203/rs.3.rs-7430586/v1
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The miRNA–immune axis in bladder cancer: systematic evidence for a new era of immunotherapy precision2025 · 1 citations
  2. 2MicroRNAs as Cancer Biomarkers: Unveiling Diagnostic and Prognostic Potential2025
  3. 3Perspectives on OncomiR and TSmiRs in Breast Cancer and Assessment of their Regulatory Network2024
  4. 4Context-Dependent miRNA Regulatory Landscapes in Breast Cancer Uncovered by Network Community Structure2025
  5. 5Regulation of B-cell development and differentiation by microRNAs during immune response and their implications in immunological disorders2025