Differential gene expression analysis shows no link between smoking and gene expression in fibroblasts and lymphocytes, suggesting further exploration needed.
Key Points
No association was found between cigarette smoke exposure and gene expression in cultured cells.
Initial results indicate differences in gene expression related to smoking across cell types and genetic backgrounds.
Differential gene expression analysis utilized RNA sequencing data from GTEx project donors for comprehensive assessment.
Future research aims to explore the impact of race and ethnicity on smoking-induced gene expression disparities.