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September 19, 2025Journal of Perinatal MedicineOpen Access

Liver fibrosis markers as predictors of adverse outcomes in pregnancy-related hypertensive disorders

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Authors

MGMurad GezerÜTÜmit TaşdemirMÖMucize Eriç Özdemir

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Overview

Retrospective study compares liver fibrosis markers in hypertensive disorders of pregnancy, indicating potential links to adverse outcomes.

Key Points

  • FIB-4 and APRI scores were significantly higher in patients with hypertensive disorders of pregnancy compared to controls.
  • FIB-4 demonstrated excellent diagnostic performance for HELLP syndrome with an AUC of 0.976.
  • Systolic blood pressure and maternal age were independent predictors of increased FIB-4 scores.
  • The predictive capacity of FIB-4 and APRI for general adverse maternal and perinatal outcomes was found to be limited.

Cite This Study

Gezer et al. (2025) studied this question.

synapsesocial.com/papers/68d435ed713b0b5dfea75d6fhttps://doi.org/10.1515/jpm-2025-0190
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