Cryptococcal Granulomatous Inflammation in Immunocompetent Pediatric Patients Presenting as Hepatic Space-occupying Lesions

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Case study reveals cryptococcosis presenting as hepatic masses in immunocompetent children, highlighting diagnostic challenges.

Cryptococcosis presenting as hepatic lesions in a 5-year-old was confirmed via antigen detection.
High-throughput sequencing showed C. neoformans at a relative abundance of 74.78%, supporting diagnosis.
Diagnostic methods using capsular polysaccharide antigen detection proved crucial in confirming cryptococcosis.
The findings suggest that hepatic cryptococcosis can mimic other conditions, emphasizing the need for accurate diagnosis.

Cao et al. (2025) studied this question.

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