Diagnostic and Prognostic Value of Myocardial Extracellular Volume Fraction Assessed Using Cardiovascular Magnetic Resonance in Patients With Restrictive Cardiac Allograft Physiology

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Discussion

Observational analysis shows ECV's prognostic significance in heart transplant patients with RCP, suggesting potential intervention timings.

Myocardial ECV values are significantly higher in patients with restrictive cardiac allograft physiology.
Receiver operating characteristic curve analysis shows ECV has a sensitivity of 60.7% and specificity of 83.3% at a cutoff of 31.5%.
Multivariate logistic regression shows an independent association between ECV and restrictive cardiac allograft physiology.
Kaplan–Meier analysis indicates higher incidences of mortality or redo heart transplant in patients with ECV ≥ 31.5%.

Tsuji et al. (2025) studied this question.

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Observational analysis shows ECV's prognostic significance in heart transplant patients with RCP, suggesting potential intervention timings.