Expression of Angiogenic and Endothelial Dysfunction Genes in Gestational Diabetes Mellitus: Focus on VEGF-A and ALOX12

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Case-control study evaluated VEGF-A and ALOX12 levels in gestational diabetes and controls, suggesting vascular dysfunction risk.

Increased expression of VEGF-A and ALOX12 was observed in gestational diabetes mellitus patients.
VEGF-A expression measured 2.65 ± 1.8 in GDM vs. 1.72 ± 1.3 in controls, highlighting its significance.
The study utilized quantitative real-time PCR to assess gene expression levels of key angiogenic factors.
Findings support potential roles of VEGF-A and ALOX12 as biomarkers for vascular risks associated with GDM.

Shaker et al. (2025) studied this question.

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View Full Paper

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Authors

Case-control study evaluated VEGF-A and ALOX12 levels in gestational diabetes and controls, suggesting vascular dysfunction risk.

Increased expression of VEGF-A and ALOX12 was observed in gestational diabetes mellitus patients.
VEGF-A expression measured 2.65 ± 1.8 in GDM vs. 1.72 ± 1.3 in controls, highlighting its significance.
The study utilized quantitative real-time PCR to assess gene expression levels of key angiogenic factors.
Findings support potential roles of VEGF-A and ALOX12 as biomarkers for vascular risks associated with GDM.

Shaker et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark