September 18, 2025Frontiers in ImmunologyOpen Access

Clinical laboratory analytes and platelet-associated parameters as surrogate markers of subclinical inflammation in latent tuberculosis infection

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Elevated laboratory parameters indicate a higher risk of latent tuberculosis infection, with erythrocyte sedimentation rate showing significant association.
Analysis revealed increased odds ratios for latent tuberculosis in individuals based on ESR, platelet distribution width, and mean platelet volume.
Cross-sectional methodology utilized to analyze blood samples from household contacts of active TB patients and healthy controls.
Implications highlight the potential of clinical laboratory markers to predict subclinical inflammation linked to LTBI.

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Implication

Cross-sectional study identifies biochemical and hematological markers associated with inflammation in latent tuberculosis infection, suggesting assessment potential.

Cite This Study

Selvavinayagam et al. (2025) studied this question.

synapsesocial.com/papers/68d434ea713b0b5dfea7464f https://doi.org/10.3389/fimmu.2025.1662454

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Implication

Cross-sectional study identifies biochemical and hematological markers associated with inflammation in latent tuberculosis infection, suggesting assessment potential.

Clinical laboratory analytes and platelet-associated parameters as surrogate markers of subclinical inflammation in latent tuberculosis infection

Key Points

Discussion

Implication

Cite This Study

Clinical laboratory analytes and platelet-associated parameters as surrogate markers of subclinical inflammation in latent tuberculosis infection

Key Points

Discussion

Implication

Cite This Study