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September 18, 2025

Post-Pandemic Shifts in Pediatric Respiratory Pathogens and Co-Infection Dynamics in Northwest China: A Large-Scale Retrospective Study from 2021 to 2025

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Authors

TLTianwei LinZWZhihua WangWCWeichao Chen

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Overview

Retrospective analysis reveals significant post-pandemic co-infections among pediatric RTI cases, suggesting urgent surveillance needs.

Key Points

  • Post-epidemic periods saw a marked increase in co-infection rates, rising from 4.05% to 11.55% across pediatric patients.
  • Human rhinovirus was the most prevalent, detected in 11.60% of cases, alongside Mycoplasma pneumoniae and HRSV.
  • Data was collected from 37,678 pediatric RTI cases in a retrospective analysis at Xi’an Children’s Hospital.
  • The findings underscore a need for improved surveillance and treatment approaches for pediatric co-infections.

Cite This Study

Lin et al. (2025) studied this question.

synapsesocial.com/papers/68d434dd713b0b5dfea73e56https://doi.org/10.21203/rs.3.rs-7467354/v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Hospitalizations trends and co-infection patterns for respiratory virus infections in children in central China 2015 to 2023: a longitudinal surveillance study2025 · 5 citations
  2. 2Epidemiological characteristics of acute viral and mycoplasma respiratory infections in Yongzhou, China: a retrospective descriptive study2025 · 5 citations
  3. 3The impact of COVID-19 pandemic on the etiological spectrum of respiratory infections in children2025
  4. 4Epidemiological trends and climatic drivers of pediatric respiratory infections in Wuhan, China: a multi-pathogen analysis2025
  5. 5Changing patterns of respiratory pathogens in hospitalized children with community-acquired pneumonia in northern China following the lifting of non-pharmaceutical interventions2025