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September 18, 2025

Long-Term Outcomes of Successful CTO PCI Using Antegrade and Retrograde Dissection and Re-entry Technique: The LOTUS study

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Authors

HGHai Feng GaoSouth China Agricultural UniversityTYTiantong YuXi'an Honghui HospitalHWHuan WangUniversity of Dundee

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Implication

This multicenter trial compares extraplaque and intraplaque tracking in CTO patients, indicating similar outcomes.

Key Points

  • Angiographic follow-up at 13 months showed similar cumulative rates of in-stent restenosis in both tracking groups.
  • The primary endpoint was binary in-segment restenosis, with secondary endpoints including major adverse cardiac events.
  • Independent predictors of in-stent restenosis included total stent length greater than 50 mm and wire crossing time over 2 hours.
  • The findings suggest that extraplaque tracking has comparable long-term outcomes to intraplaque tracking techniques.

Cite This Study

Gao et al. (2025) studied this question.

synapsesocial.com/papers/68d433b0713b0b5dfea7347dhttps://doi.org/10.1101/2025.09.10.25335543
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