Retrospective analysis highlights the effectiveness of PBSC apheresis in children with malignant neoplasms, suggesting methods to enhance safety and efficiency.
Key Points
PBSC apheresis shows effectiveness and safety for hematopoietic stem cell collection in young patients with malignant neoplasms.
Among 97 patients, the median CD34+ cell count at apheresis was 100.5 cells/µl, indicating good mobilization outcomes.
Factors influencing efficiency include lower body weight and higher CD34+ cell numbers, suggesting a need for optimized preparation strategies.
No complications were observed, emphasizing the importance of adequate preparation and risk prediction in apheresis procedures.