Sabinene confers protection against cerebral ischemia in rats: potential roles of antioxidants, anti-inflammatory effects, and astrocyte-neurotrophic support
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Key Points
Sabinene significantly improved motor and cognitive impairments caused by cerebral ischemia in rats.
The treatment increased levels of antioxidants and reduced harmful substances in key brain regions after ischemic stroke.
Sabinene reduced harmful acetylcholinesterase activity, boosting brain-derived neurotrophic factor across all the assessed areas.
The study highlights sabinene's potential in attenuating astrocytic dysfunction and aiding neuroprotection after stroke.
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Implication
Research demonstrates sabinene enhances antioxidants and reduces inflammation in rats, suggesting neuroprotective benefits.