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September 18, 2025Journal of Clinical Gastroenterology

Monoclonal Antibodies for Eosinophilic Esophagitis and Gastritis

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Authors

QIQunoot IrfanSZSyed Muhammad Mehdi ZaidiMAMustafa Hassan Alvi

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Overview

Systematic review assesses monoclonal antibodies in eosinophilic esophagitis and gastritis, showing benefits.

Key Points

  • Monoclonal antibodies significantly reduced peak eosinophil count in eosinophilic esophagitis.
  • The meta-analysis included eight RCTs with 865 participants, demonstrating strong results for dupilumab.
  • A systematic review along with meta-analysis followed PRISMA guidelines to ensure rigorous evaluation.
  • The findings call for larger trials to further confirm findings and examine long-term effects.

Cite This Study

Irfan et al. (2025) studied this question.

synapsesocial.com/papers/68d433aa713b0b5dfea73027https://doi.org/10.1097/mcg.0000000000002249
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