Dose-response relationship between the triglyceride-glucose index and metabolic syndrome risk in patients with type 2 diabetes: a cross-sectional analysis of 1,560 cases
Cross-sectional analysis reveals significant dose-response relationship in patients with type 2 diabetes, indicating relevant biomarker for metabolic syndrome risk.
Key Points
The TyG index is a significant predictor of metabolic syndrome (MS) risk in patients with type 2 diabetes (T2DM).
A nonlinear dose-response relationship was observed, with MS risk increasing after TyG index levels exceeded 9.31.
Multivariable logistic regression analysis revealed higher risk of MS in patients with higher TyG quartiles (Q4 group OR=26.994).
ROC curve analysis showed an area under the curve (AUC) of 0.793 for TyG index's predictive performance regarding MS.