September 17, 2025Open Access

Parallel but distinct adaptive routes in the budding and fission yeasts after 10,000 generations of experimental evolution

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Comparative analysis reveals divergent evolutionary dynamics in fission and budding yeasts, suggesting adaptive mechanisms vary significantly.

Fission yeast populations evolved distinct adaptations to hypoxic stress, unlike budding yeast adaptations.
Most fission yeast showed an increased sensitivity to oxidative stress while adapting, highlighting evolutionary trade-offs.
Experimental evolution using identical conditions for both yeast species unveiled different genes driving adaptation.
Findings underscore the role of contingency in evolutionary outcomes despite shared environments and similar genomic content.

N’Guessan et al. (2025) studied this question.

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Comparative analysis reveals divergent evolutionary dynamics in fission and budding yeasts, suggesting adaptive mechanisms vary significantly.