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September 17, 2025Bangladesh Journal of MedicineOpen Access

L-Asparaginase Associated Toxicities In Children With Acute Lymphoblastic Leukemia: A Single-center Prospective Cohort Study

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Authors

YJYesmin Tanjin JahanOBOlia Sharmeen BatenWNWaheeda Nargis

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Overview

Prospective cohort study identifies l-asparaginase toxicities in children with acute lymphoblastic leukemia, suggesting hyperglycemia as a key concern.

Key Points

  • Hyperglycemia was the most common toxicity identified in children with acute lymphoblastic leukemia.
  • Patients over 10 years old with high WBC counts showed an increased risk of toxicity during the study.
  • This prospective cohort study analyzed 71 children diagnosed with acute lymphoblastic leukemia for toxicities over two years.
  • Identifying these toxicities allows healthcare providers to better manage treatments for children with acute lymphoblastic leukemia.

Cite This Study

Jahan et al. (2025) studied this question.

synapsesocial.com/papers/68d42f69713b0b5dfea70e8fhttps://doi.org/10.3329/bjm.v36i3.81979
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