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September 17, 2025Open Access

Impact evaluation of an antimicrobial stewardship team intervention based on AWaRe guidelines: a single- center, cohort, interrupted-time series study

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Authors

YYYusuke YagiYAYu ArakawaYHYukihiro Hamada

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Overview

Cohort study shows significant shift to Access antibiotics in outpatient prescriptions, indicating stewardship success.

Key Points

  • The intervention increased the usage proportion and defined daily doses of Access antibiotics, suggesting effectiveness.
  • Statistically significant results included a rise in Access antibiotics (p = 0.02) and a decline of Watch antibiotics (p = 0.02).
  • Longitudinal analysis displayed a shift in prescribing behavior, emphasizing the importance of targeted educational interventions.
  • Resistance patterns in Escherichia coli highlight the need for prescribers to consult local antibiograms for informed decision-making.

Cite This Study

Yagi et al. (2025) studied this question.

synapsesocial.com/papers/68d42c58713b0b5dfea6fc72https://doi.org/10.21203/rs.3.rs-7514843/v1
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