This review explores metabolic pathways altered in cancer cells, suggesting targets for cancer therapeutics and metabolic adaptations influencing treatment resistance.
Key Points
Cancer metabolism involves unique alterations in metabolic pathways, enabling rapid proliferation of cancer cells.
Key metabolic processes altered include glycolysis, amino acid transport, and lipid intake, which facilitate sustained high energy demand.
Modifications in nucleotide metabolism and resistance to therapies reflect the adaptive mechanisms in cancer cells.
Targeting these metabolic pathways presents opportunities and challenges in developing effective cancer therapeutics.