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September 17, 2025World Journal of Advanced Engineering Technology and Sciences

Molecular erasers: Reprogramming cancer immunity through protein degradation

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Authors

AMAsif Hassan MalikMRMd. Shafiur Rahman

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Overview

This review highlights advances in targeted protein degradation and its applications in cancer immunotherapy.

Key Points

  • Targeted protein degradation technologies are advancing cancer treatments by effectively eliminating disease-associated proteins.
  • Recent methods like PROTACs and molecular glues enhance the potential of immunotherapies targeting key regulators in cancer.
  • Challenges include bioavailability and delivery strategies that need to be addressed for effective clinical applications.
  • Integrating nanotechnology and computational modeling presents future opportunities in enhancing TPD-based immunotherapy.

Cite This Study

Malik et al. (2025) studied this question.

synapsesocial.com/papers/68d42c51713b0b5dfea6f889https://doi.org/10.30574/wjaets.2025.16.3.1335
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