September 17, 2025Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition

Effects of Aging on Cerebral Morphology and Microstructure in Rhesus Macaques

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Age-related brain volumetric atrophy was found particularly in cortico-striatal regions, indicating specific structural vulnerabilities.
Widespread changes in diffusion metrics across white matter regions suggest extensive microstructural modifications with aging.
High-resolution neuroimaging allowed for sensitive analyses of brain morphology, facilitating better detection of age-related changes.
Findings reinforce the macaque model's relevance for understanding normative human aging and its associated brain alterations.

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Implication

Cross-sectional analysis examines aging impacts on cerebral morphology and microstructure in rhesus macaques, suggesting widespread changes by mid-adulthood.

Cite This Study

Grigorian et al. (2025) studied this question.

synapsesocial.com/papers/68d42934713b0b5dfea6e6f2 https://doi.org/10.58530/2025/1507

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Implication

Cross-sectional analysis examines aging impacts on cerebral morphology and microstructure in rhesus macaques, suggesting widespread changes by mid-adulthood.

Effects of Aging on Cerebral Morphology and Microstructure in Rhesus Macaques

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Discussion

Implication

Cite This Study

Effects of Aging on Cerebral Morphology and Microstructure in Rhesus Macaques

Key Points

Discussion

Implication

Cite This Study

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