September 17, 2025Biomolecules and BiomedicineOpen Access

Procalcitonin in acute and chronic coronary syndromes: Diagnostic biomarker of coronary inflammation

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Discussion

Retrospective analysis assesses procalcitonin's role in diagnosing acute and chronic coronary syndromes, highlighting its diagnostic performance.

Procalcitonin levels significantly differ among ACS, CCS, and controls, indicating its utility as a diagnostic biomarker.
Log10-transformed procalcitonin levels independently predict the presence of disease in both acute and chronic coronary syndromes.
Receiver operating characteristic analyses show moderate diagnostic accuracy for procalcitonin in both ACS and CCS at specified cut-offs.
Procalcitonin correlates with SYNTAX scores in CCS, yet lacks strong prognostic associations in ACS despite showing potential diagnostic value.

Sakarya et al. (2025) studied this question.

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Retrospective analysis assesses procalcitonin's role in diagnosing acute and chronic coronary syndromes, highlighting its diagnostic performance.