Dissecting the mechanisms of MASLD fibrosis in the era of single-cell and spatial omics

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Exploring fibrosis mechanisms in masld reveals critical cellular interactions and regulatory pathways involved.
New technologies highlight the roles of epithelial cell plasticity and macrophage accumulation in liver fibrosis.
Single-cell and spatial omics techniques enhance understanding of varying fibrosis mechanisms across patients.
These insights could inform targeted antifibrotic therapies tailored to individual patient profiles.

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This review discusses insights from single-cell and spatial omics in fibrosis regulation in masld, implying new therapeutic strategies.

Colella et al. (2025) studied this question.

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