Association With Incidence of Ischemic Heart Disease Based on the Estimated Glomerular Filtration Rate in the Population of the Three Southern Border Provinces of Thailand

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Retrospective cohort study shows eGFR reduction raises ischemic heart disease risk in adults, suggesting vital implications.

Reduced eGFR increases risk of ischemic heart disease, with significant findings noted in adults aged 30 and older.
Among 16,763 participants, a cumulative incidence of 4.5% for IHD and an incidence density of 13.98 cases per 1,000 person-years were observed.
Cox regression analysis indicated a graded increase in IHD risk across lower eGFR groups, with adjusted HRs ranging from 1.89 to 4.96.
Higher systolic blood pressure and older age were also key risk factors, while elevated HDL-C levels were linked to reduced IHD risk.

Ngoh et al. (2025) studied this question.

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