This research demonstrates cytotoxicity of gold nanoparticles in cancer cells, suggesting optimization in biomedical uses.
Key Points
Gold nanoparticles synthesized using Streptomyces sp. YJD18 showed dose-dependent cytotoxicity against various cancer cells, with optimal effects at 30 μg/mL.
Formation of gold nanoparticles was confirmed by color change and specific UV–Vis absorption, with size distribution measured at 20–30 nm.
Analysis through techniques like TEM and DLS revealed the nanoparticles are irregular, polycrystalline spheres with good dispersity and surface properties.
The findings indicate significant biomedical potential of the synthesized gold nanoparticles for applications in cancer therapy and wound healing.