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September 16, 2025Asian Journal of Pharmaceutical and Clinical ResearchOpen Access

Monitoring Antimicrobial Resistance Among Intensive Care Unit Gram-Negative Isolates: Insights From a Retrospective Study

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Authors

RSRajni SharmaJCJyoti ChauhanAMAshwini Manhas

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Overview

Retrospective study reveals shifting resistance profiles of gram-negative bacteria in ICUs, highlighting alarming trends.

Key Points

  • The study found a marked increase in extensively drug-resistant bacteria, rising from 16.89% in 2023 to 55.46% in 2024.
  • Klebsiella spp. was the most frequently isolated organism, comprising 42.8% of gram-negative isolates across two years.
  • A decrease in multidrug-resistant bacteria was observed, dropping from 36.42% in 2023 to 11.76% in 2024, suggesting changing resistance patterns.
  • Respiratory samples were the predominant source for gram-negative bacteria, especially in the Medicine ICU and Neuro ICU settings.

Cite This Study

Sharma et al. (2025) studied this question.

synapsesocial.com/papers/68d42321713b0b5dfea6abe3https://doi.org/10.22159/ajpcr.2025v18i9.55898
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