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September 16, 2025Open Access

Insights into Persistent SARS-CoV-2 Reservoirs In Chronic Long-COVID

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Authors

SPSwayam PrakashSKSweta KaranYLYassir Lekbach

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Overview

Review highlights persistent viral RNA reservoirs in long-covid patients, suggesting a link to chronic inflammation.

Key Points

  • Persistent reservoirs of SARS-CoV-2 and viral RNA may drive chronic long-covid symptoms.
  • Long-covid affects 10 to 20 million in the U.S., presenting over 200 diverse symptoms across organ systems.
  • Animal models are explored to understand virus reservoirs and develop therapeutic strategies for long-covid.
  • Understanding these reservoirs could alleviate chronic inflammation, improving the quality of life for patients.

Cite This Study

Prakash et al. (2025) studied this question.

synapsesocial.com/papers/68d4218f713b0b5dfea69863https://doi.org/10.20944/preprints202509.1120.v1
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