September 16, 2025mSphereOpen Access

Repeated thermal stress exposure in Aedes aegypti co-infected with Wolbachia and dengue virus

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Observational analysis reveals reduced thermal tolerance in Aedes aegypti, indicating implications for Wolbachia-based vector control.

Co-infection with Wolbachia and DENV leads to significantly increased thermal sensitivity in Aedes aegypti.
Mosquitoes exposed to heat stress exhibit a twofold faster median knockdown time than uninfected controls.
Repeated thermal stress exposure does not enhance the effects of infection on thermal susceptibility.
Extended thermal stress significantly reduces dengue virus loads while stabilizing Wolbachia levels.

Ser et al. (2025) studied this question.

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