Hematological and biochemical alterations in school-aged children with sickling cell disorders indicate an elevated risk of liver and cardiovascular diseases
Cross-sectional analysis reveals significant biochemical and hematological changes in children, indicating elevated risks for cardiovascular and liver diseases.
Key Points
Sickling cell disorder patients exhibit significant hematological alterations, suggesting increased risks for various diseases.
Biochemical markers show higher triglyceride levels and lower HDL cholesterol, indicating cardiovascular disease risk.
Liver enzymes and bilirubin levels are elevated in sickling cell disorder patients, pointing to a potential liver disease risk.
The study utilized a cross-sectional design, comparing 60 sickling cell disorder patients with 50 control subjects for 6 months.