This study develops a multifunctional hydrogel that scavenges reactive oxygen species and restores electrical conduction in cardiomyocytes, suggesting a new MI therapy approach.
Key Points
The multifunctional hydrogel shows improved cytoprotection against oxidative stress and enhances cardiac function.
The integrated PEDOT@PMOF nanofiller effectively scavenges reactive oxygen species and restores electrical signal coupling.
Cardiomyocyte calcium transients were significantly enhanced, reflecting better cellular recovery and function.
This innovative hydrogel approach indicates a promising strategy for future therapies targeting myocardial infarction.