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September 14, 2025Journal of Biomaterials ApplicationsOpen Access

Injectable hydrogels loaded with EGCG /KGN for the treatment of osteoarthritis

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Authors

JZJie ZhouLJLiang JiaoKYKun Yang

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Overview

This research develops hydrogels delivering EGCG and KGN, improving cartilage differentiation in osteoarthritis.

Key Points

  • The double-loaded hydrogels effectively reduce inflammation and oxidative stress in osteoarthritis.
  • Hydrogels show excellent shear-thinning properties, facilitating injection into the joint cavity.
  • Encapsulation of EGCG and KGN supports BMSC differentiation, aiding in extracellular matrix maintenance.
  • These innovations propose early minimally invasive strategies for managing osteoarthritis symptoms.

Cite This Study

Zhou et al. (2025) studied this question.

synapsesocial.com/papers/68d42047713b0b5dfea68ab4https://doi.org/10.1177/08853282251379151
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