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September 14, 2025Biomechanics and Modeling in MechanobiologyOpen Access

Inverse analysis of patient-specific parameters of a 3D–0D closed-loop cardiovascular model with an exemplary application to an adult tetralogy of Fallot case

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Authors

TATahar ArjouneCBChristian BilasCMChristian Meierhofer

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Overview

Inverse analysis identifies 3D-0D cardiovascular parameters in tetralogy of Fallot patients, highlighting model reliability.

Key Points

  • The framework accurately predicts physiological changes in a tetralogy of Fallot patient after valve intervention.
  • Measurements from flow, pressure, and cardiac MRI are used to optimize the 3D-0D cardiovascular model effectively.
  • Decomposing the nonlinear inverse problem into simpler subproblems enhances computation speed and accuracy.
  • The model's predictions align closely with postoperative measurements, validating its application in clinical decision-making.

Cite This Study

Arjoune et al. (2025) studied this question.

synapsesocial.com/papers/68d42047713b0b5dfea68a79https://doi.org/10.1007/s10237-025-02006-w
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