September 13, 2025Journal of Global HealthOpen Access

Age-period-cohort analysis of cardiovascular disease trends in middle-aged and older adults: cross-country comparison across HRS, ELSA, SHARE, and CHARLS

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Discussion

Cross-country comparison reveals significant age and period effects on cardiovascular disease risk trends, highlighting regional differences.

CVD risk significantly increases with age, peaking at age 75 in China and continuously rising elsewhere.
Subgroup analyses indicate that social-demographic factors like gender and education moderate CVD risk trends across regions.
Bayesian inference methods were used to model age, period, and cohort effects on CVD risk across the USA, UK, Europe, and China.
The findings suggest tailored public health interventions are necessary to reduce the CVD burden effectively across different demographic groups.

Li et al. (2025) studied this question.

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Cross-country comparison reveals significant age and period effects on cardiovascular disease risk trends, highlighting regional differences.