September 12, 2025NeuroscienceOpen Access

Effect of electro-acupuncture on motor dysfunction in middle cerebral artery occlusion/reperfusion rats though cortex-striatum somatostatin neural circuit

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Electro-acupuncture at LI11 and ST36 greatly improved motor function in rats with motor dysfunction caused by MCAO.
The study found significant enhancement in the modified neurological severity score after electro-acupuncture treatment.
Detailed examination revealed changes in the GABAergic system, indicating its role in locomotion regulation post-stroke.
Findings highlight potential mechanisms like synaptic plasticity involving the CS-SST neural circuit in improving motor function.

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Observational analysis revealed improved motor function in MCAO/R rats after electro-acupuncture, suggesting neural circuit involvement.

Zheng et al. (2025) studied this question.

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