September 12, 2025Open Access

Cortical-layer EEG-fMRI at 7T: experimental setup and analysis pipeline to elucidate generating mechanisms of alpha oscillations

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Findings reveal significant negative correlations between EEG alpha power and BOLD signal in visual cortex.
In 9 out of 10 participants, the analysis showed depth-dependence in alpha-BOLD correlations after deveining.
Layer fMRI at 7T allows for exploring cortical responses across depths, confirming the potential of non-invasive techniques.
This method enhances understanding of alpha oscillations in humans, indicating top-down processes during cognitive tasks.

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This work demonstrates new insights into alpha oscillation generation using EEG and fMRI, suggesting depth-specific processes in humans.

Marsh et al. (2025) studied this question.

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