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September 12, 2025Frontiers in EndocrinologyOpen Access

Triglyceride-glucose index as a novel prognostic biomarker for coronary artery disease: evidence from a large-scale prospective cohort study

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Authors

BFBaoyu FengYZYejing ZhaoWXWei Xu

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Overview

Prospective cohort study reveals correlations between triglyceride-glucose index and mortality risks in CAD patients, suggesting its prognostic value.

Key Points

  • Higher triglyceride-glucose index correlates with increased risks of all-cause death and cardiovascular disease death in coronary artery disease patients.
  • The study showed a 1.34-fold risk increase for all-cause death and a 1.99-fold increase for cardiovascular disease death in the highest triglyceride-glucose index tertile.
  • Cox proportional hazards models indicated that the triglyceride-glucose index is an independent risk factor for all-cause death and cardiovascular disease death.
  • Findings suggest that the triglyceride-glucose index is a robust biomarker for cardiovascular risks, particularly in patients with chronic coronary syndrome.

Cite This Study

Feng et al. (2025) studied this question.

synapsesocial.com/papers/68d41d9b713b0b5dfea668f1https://doi.org/10.3389/fendo.2025.1653948
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