Impact of subclinical hypothyroidism on clinical, hormonal, and metabolic parameters in women with polycystic ovary syndrome: the role of levothyroxine therapy

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Subclinical hypothyroidism is found in 31.7% of women with polycystic ovary syndrome, impacting various parameters.
Untreated subclinical hypothyroidism has a higher median fasting blood sugar compared to treated cases, with distinct metabolic outcomes.
Participants treated with levothyroxine exhibit improved hormonal levels and reduced prevalence of clinical symptoms like acne.
Significant correlations exist between thyroid-stimulating hormone levels and blood pressure in treated groups, emphasizing clinical implications.

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Cross-sectional analysis highlights hormonal and metabolic changes in women with PCOS, indicating levothyroxine benefits.

Qasim et al. (2025) studied this question.

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