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September 12, 2025Diabetes Metabolic Syndrome and ObesityOpen Access

Obesity and Its Comorbidities: Current Treatment Options, Emerging Biological Mechanisms, Future Perspectives and Challenges

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Authors

LWLihua WangQWQian WangYXYing Xiong

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Overview

This review analyzes obesity-related conditions and the effectiveness of metabolic bariatric surgery, suggesting new therapeutic approaches.

Key Points

  • Obesity is linked to severe comorbidities, significantly increasing risks of type 2 diabetes and cardiovascular diseases.
  • Metabolic bariatric surgery is the most effective intervention for long-term weight loss but is limited to advanced cases.
  • Emerging insights identify novel biological mechanisms that drive obesity and highlight potential therapeutic targets.
  • Understanding signal transduction pathways could lead to innovative strategies in precision medicine for obesity management.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68d41c02713b0b5dfea65367https://doi.org/10.2147/dmso.s540103
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