September 12, 2025Journal of Clinical MedicineOpen Access

miR-197, miR-101, and miR-143 and Pro-Inflammatory Cytokines in Migraine

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Discussion

Observational analysis shows elevated microRNA levels in chronic migraine, suggesting inflammation plays a role in migraine management.

hsa-miR-197-3p levels are significantly elevated in migraine patients without aura compared to those with aura.
Chronic migraine patients show higher levels of IL-17 and IL-6, indicating a persistent inflammatory response associated with this condition.
This analytical study utilized ELISA and qPCR methodologies to measure inflammatory markers and microRNAs in migraine subjects.
Findings may support further research into the role of inflammatory markers in migraine pathophysiology.

Gómez et al. (2025) studied this question.

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