September 12, 2025BioengineeringOpen Access

The Therapeutic Scope of Orofacial Mesenchymal Stem Cells

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This review outlines the roles of orofacial mesenchymal stem cells in craniofacial repair and their immunomodulatory functions.

Orofacial mesenchymal stem cells have shown promise in tissue regeneration, especially for craniofacial repair.
These stem cells can be sourced ethically from discarded tissues, like exfoliated deciduous teeth, reducing donor site morbidity.
OMSCs possess unique advantages, including high proliferation and multi-differentiation capacity for various tissue applications.
The immunomodulatory properties of OMSCs allow them to regulate inflammation through cytokine secretion.

Vaddaram et al. (2025) studied this question.

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