Non-conventional lipid parameters predict the risk of rapid kidney function decline in patients with cardiovascular-kidney-metabolic syndrome: The first cohort study evidence from CHARLS
Cohort study reveals significant association between novel lipid biomarkers and rapid kidney decline in CKM syndrome patients, indicating potential for better risk assessment.
Key Points
A 19% increased risk of rapid kidney function decline is linked to higher non-HDL-to-HDL cholesterol ratio.
The natural logarithm of remnant cholesterol and cholesterol index showed risks increasing by 112% and 125%, respectively.
Logistic regression models revealed these lipid parameters as strong predictors for renal function deterioration in CKM patients.
Receiver operating characteristic curve analysis demonstrated enhanced predictive capacity for these lipid-derived biomarkers.